Table 1.

Kinetic parameters of motile structures containing tau-EGFP or α-synuclein–EGFP in transfected rat cortical neurons

Rate between pauses* [Range] (mm/day) Time moving (% of total) Time pausing (% of total) Time moving anterograde (% of total) Time moving retrograde (% of total)
Tau 31.4±0.8 (n=193) [14-124] 27 73 57 43
α-Synuclein 161±5 (n=185) [111-645] 20 80 48 52
  • The movement characteristics of individual fluorescent structures containing tau-EGFP or α-synuclein—EGFP were measured 48 hours after transfection of rat cortical neurons.

  • * Rates are shown as mean±s.e.m. (n), where n=number of periods of movement detected.

  • n=number of structures observed (tau, n=17; α-synuclein, n=19).