Table 2.

Cholesterol:phospholipid ratios of different secretory vesicles

Species and tissue Type Vesicle PM§
Bovine adrenal medulla (Blaschko et al., 1967) CG 0.53±0.08 -
Bovine adrenal medulla (DaPrada M. et al., 1972) CG 0.40±0.03
Bovine adrenal medulla (Dreyfus et al., 1977) CG 0.53±0.05 -
Bovine adrenal medulla (Zinder et al., 1978) CG 1.04 0.64
Ox pancreas (White and Hawthorne, 1970) ZG 0.56 -
Guinea Pig pancreas (Meldolesi et al., 1971) ZG 0.55±0.06 0.51±0.03
Bovine mammary gland (Keenan et al., 1979) SecV 0.34±0.01 -
Bovine splenic nerve trunk (Lagercrantz, 1971) DCG 0.50±0.08 -
Rat brain (adult) (Breckenridge et al., 1973) SV 0.58±0.09 -
Guinea Pig cereberal cortex (Baker et al., 1975) SV 0.50±0.04 -
Guinea Pig cerebellar cortex (Nagy et al., 1976) SV 0.51±0.06 -
Ray (Narcine brasiliensis) electric organ (Deutsch and Kelly, 1981) SV 0.500±0.043 -
Ray (Torpedo marmorata) electric organ (Baker et al., 1975) SV 0.42±0.04 -
Ray (Torpedo marmorata) electric organ (Nagy et al., 1976) SV 0.42±0.04 -
Ray (Torpedo marmorata) electric organ (Michaelson et al., 1983) SV 0.63 -
Urchin (Lytechinus variegatus) oocyte (Decker and Kinsey, 1983) CV 1.33±0.12 0.55±0.14
Urchin (Strongylocentrotus purpuratus) oocyte CV 0.602±0.034 -
  • Type of vesicle: CG, chromaffin granule; ZG, zymogen granule; SecV, secretory vesicle; DCG, dense core granule; SV, synaptic vesicle; CV, cortical vesicle.

  • Molar cholesterol:phospholipid ratio of secretory vesicles.

  • § Molar cholesterol:phospholipid ratio of plasma membrane.