Table 1.

Names used in different organisms for the factors involved in central spindle and contractile ring assembly/dynamics during cytokinesis

Mammals DrosophilaCaenorhabditis elegans Function
Aurora B Aurora B AIR-2 Kinase
CIT-K STI/DCK Absent Kinase
CLASP ORBIT/MAST CLS-2 MAP
ECT-2 PBL LET-21 GEF
INCENP INCENP ICP-1 Centromeric protein
HKIF-4 KLP3A KLP19 KLP
KIF18 KLP67A Unknown KLP
MgcRacGAP RacGAP50C CYK-4 GAP
MKLP-1/2 CHO1 PAV ZEN-4 KLP
Plk1 Polo PLC1/2 Kinase
PRC1 FEO SPD-1 (?)* MAP
ROCK ROK LET-502 Kinase
  • Abbreviations: GEF, GTP guanine nucleotide exchange factor; GAP, GTPase-activating protein; KLP, kinesin-like protein; MAP, microtubule-associated protein.

  • * The question mark indicates that the functional correspondence between SPD-1 and PRC-1 is still uncertain.