Table 1.

Gene profile for AP subunits after treatment of human melanocytes with DKK1

Description* Fold difference DKK1 stimulated Unstimulated
AP4, β1 2.90 708 244
AP2, α1, transcript variant 2 1.75 13952 7951
GAP3, β2 1.73 2047 1180
AP1, γ1 1.51 9483 6253
AP2, σ1, transcript variant AP17 1.45 114745 78886
AP1, μ2 1.44 1580 1096
AP1, σ3 1.39 1635 1170
AP1, σ1, transcript variant 2 1.38 44659 32257
AP3, μ1, transcript variant 2 1.35 16436 12167
AP2, β1 1.33 45241 34111
AP3, σ1, transcript variant 1 1.15 28072 24332
AP1, β1, transcript variant 2 1.11 6649 5984
AP1, σ2 1.07 170783 159244
AP4, μ1 1.02 3036 2961
AP3, σ2 1.00 4031 4010
AP4, β1 0.97 943 971
AP1, γ2, transcript variant 1 0.87 2070 2386
AP2, μ1 0.80 78539 98451
AP1, μ1 0.78 17410 22235
AP3, σ2 0.78 5378 6894
AP4, ϵ1 0.70 1225 1747
AP3, μ2 0.69 16251 23540
AP4, σ1 0.69 792 1153
AP2, α2 0.66 4517 6885
AP3, β1 0.61 11335 18478
AP3, δ1 0.57 43877 76592
  • * Greek characters indicate AP family subunits

  • Values above 1.4 are considered upregulated; values below 0.7 are considered downregulated