Table 2.

Predicted intracellular phosphorylation sites

Pannexin Position Context Domain Score* Predicted residue
Panx1 159 KAAKSARDL Intracellular loop 0.99 S
Panx1 206 KKNSSHLIM Intracellular loop 0.73 S
Panx1 328 YNDLSLYNL Carboxyl tail 0.58 S
Panx1 343 SELKSYKCL Carboxyl tail 0.99 S
Panx1 394 EDQGSQRVE Carboxyl tail 0.92 S
Panx1 405 DLDLSSEAA Carboxyl tail 0.98 S
Panx1 387 TSLQTKGED Carboxyl tail 0.78 T
Panx1 10 LATEYVFSD N-terminus 0.72 Y
Panx1 192 SHFKYPIVE Intracellular loop 0.66 Y
Panx1 324 KSEGYNDLS Carboxyl tail 0.94 Y
Panx3 23 DRRGSRLKG N-terminus 0.99 S
Panx3 150 ELDKSYNRS Intracellular loop 0.96 S
Panx3 167 QIRQSSSDP Intracellular loop 0.99 S
Panx3 168 IRQSSSDPH Intracellular loop 0.93 S
Panx3 303 KGLLSIYEM Carboxyl tail 0.96 S
Panx3 315 FDLLSRKML Carboxyl tail 0.57 S
Panx3 342 SELISFSWL Carboxyl tail 0.5 S
Panx3 357 KDTTTQKHN Carboxyl tail 0.66 T
Panx3 364 HNIDTVVDF Carboxyl tail 0.88 T
Panx3 186 RKERYFEFP Intracellular loop 0.95 Y
  • * Phosphorylation score (NetPhos 2.0 Server). Max.=1.0