Table 2.

Nuclear morphometric-parameter analysis of WT and Nesprin-2-Giant-silenced cells

Area (μm2) Perimeter (μm) Contour ratio
WT 170.4±9.8 49.3±2.9 0.87±0.05
Nesprin-2 Giant RNAi 191.9±11.1 57.5±3.3 0.73±0.04
P value 2.03×10–7 1.6×10–121 3.34×10–47
  • Mean ± s.e.m. results and the corresponding P values (control versus mutant) are indicated. Measurements were performed in duplicate experiments and 300 cells were counted for each cell type