Table 1.

Population analysis of RANK in CD45+CD11b+CD115+ osteoclastic precursors of wild-type, Ccr1-deficient and Cx3cr1-deficient mice

CD45+ (%)CD11b+CD115+(%)CD11bhi (%)CD11blo (%)
Wild-type87.73±4.2813.40±0.9510.99±0.941.89±0.55
CCR1KO91.75±2.339.67±0.43*8.26±0.30*0.63±0.09*
CX3CR1KO91.93±1.5314.35±1.9013.00±1.981.01±0.02*
  • Population ratio of CD11bhi (R1-gated) subpopulation and CD11blo (R2-gated) subpopulation of CD11b+CD115+ osteoclastic precursors (in Fig. 5) is shown as mean percentage ± s.e.m. (n = 3). *Statistically significant (P<0.05), based on post-hoc test of one-factor factorial ANOVA.