Actin polymerization
- Concerted regulation of actin polymerization during constitutive secretion by cortactin and PKD2
Highlighted Article: Phosphorylation of cortactin by PKD2 at S298 controls the N-WASP-mediated synergistic actin polymerization required for constitutive secretion from the TGN by modulating WIP-dependent sequestration of N-WASP.
- NKG2D–DAP10 signaling recruits EVL to the cytotoxic synapse to generate F-actin and promote NK cell cytotoxicity
Summary: The NK activating receptor NKG2D–DAP10 recruits EVL to the cytotoxic synapse via a Grb2–VAV1 signaling node to promote F-actin generation, target cell adhesion and the development of cell-mediated cytotoxicity.
- Actin-mediated movement of chloroplasts
Summary: A review of the photo-relocation movement of chloroplasts, which is mediated by newly discovered chloroplast actin filaments that are localized at the leading edge of moving chloroplasts.