Adaptor protein
- Cargo-mediated recruitment of the endocytic adaptor protein Sla1 in S. cerevisiae
Highlighted Article: Cooperation between cargo binding and interaction with other endocytic coat proteins is essential for adaptor protein recruitment to the membrane.
- ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters
Highlighted Article: During T cell activation, a cytoskeletal pool of ADAP enters nascent contacts in advance of other adaptors and enhances contact stability and TCR signaling by participating in multivalent signaling complexes.