Adipose tissue
- Constitutive P2Y2 receptor activity regulates basal lipolysis in human adipocytes
Summary: Here, using pharmacological antagonism or knockdown of P2Y2 receptors, we show that basal lipolysis and adipokine secretion are controlled by autocrine purinergic signalling via P2Y2 receptors in human adipocytes.
- miR-450a-5p within rat adipose tissue exosome-like vesicles promotes adipogenic differentiation by targeting WISP2
Summary: Exosome-like vesicles derived from adipose tissue promote adipogenesis through miR-450a-5p by targeting WISP2. This suggests that exosome-like vesicles can be involved in cell-to-cell communication during adipocyte differentiation.