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Bone resorption

  • RESEARCH ARTICLE
    Catabolic activity of osteoblast lineage cells contributes to osteoclastic bone resorption in vitro
    Dinisha Cyril Pirapaharan, Jacob Bastholm Olesen, Thomas Levin Andersen, Sandra Bjerre Christensen, Per Kjærsgaard-Andersen, Jean-Marie Delaisse, Kent Søe
    Journal of Cell Science 2019 132: jcs229351 doi: 10.1242/jcs.229351 Published 15 May 2019

    Summary: Osteoblast lineage cells directly stimulate osteoclastic bone resorption and promote the aggressive trench-resorption mode by exerting a matrix metalloproteinase-dependent catabolic activity.

  • RESEARCH ARTICLE
    Time-lapse reveals that osteoclasts can move across the bone surface while resorbing
    Kent Søe, Jean-Marie Delaissé
    Journal of Cell Science 2017 130: 2026-2035; doi: 10.1242/jcs.202036

    Summary: Bone erosion requires that osteoclasts both resorb and migrate. According to common belief, these activities are mutually exclusive and alternate. Paradoxically, we show here simultaneous resorption and migration.

  • RESEARCH ARTICLE
    Roles of chemokine receptor CX3CR1 in maintaining murine bone homeostasis through the regulation of both osteoblasts and osteoclasts
    Akiyoshi Hoshino, Satoshi Ueha, Sanshiro Hanada, Toshio Imai, Masako Ito, Kenji Yamamoto, Kouji Matsushima, Akira Yamaguchi, Tadahiro Iimura
    Journal of Cell Science 2013 126: 1032-1045; doi: 10.1242/jcs.113910
  • RESEARCH ARTICLE
    Activation of P2X7 receptors causes isoform-specific translocation of protein kinase C in osteoclasts
    Souzan Armstrong, Alexey Pereverzev, S. Jeffrey Dixon, Stephen M. Sims
    Journal of Cell Science 2009 122: 136-144; doi: 10.1242/jcs.031534

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