Caveolin
- PTK7 localization and protein stability is affected by canonical Wnt ligands
Summary: In the presence of canonical Wnt proteins, the regulator of planar cell polarity PTK7 is endocytosed and degraded in lysosomes. By contrast, PTK7 inhibits canonical Wnt signaling suggesting a mechanism of mutual inhibition.
- Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly
Highlighted Article: The assembly of respiratory syncytial virus occurs in caveolar membranes and caveolar coat components are incorporated into the viral envelope.
- Architecture of the caveolar coat complex
Highlighted Article: This paper reports the first structural analysis of the entire caveolar protein coat isolated intact from mammalian cells, and shows that the coat is composed of two morphologically distinct layers.