Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Accepted manuscripts
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Special issues
    • Subject collections
    • Cell Scientists to Watch
    • First Person
    • Sign up for alerts
  • About us
    • About JCS
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Fast-track manuscripts
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • JCS Prize
    • Manuscript transfer network
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contacts
    • Contact JCS
    • Subscriptions
    • Advertising
    • Feedback
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

User menu

  • Log in

Search

  • Advanced search
Journal of Cell Science
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

supporting biologistsinspiring biology

Journal of Cell Science

  • Log in
Advanced search

RSS   Twitter  Facebook   YouTube  

  • Home
  • Articles
    • Accepted manuscripts
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Special issues
    • Subject collections
    • Cell Scientists to Watch
    • First Person
    • Sign up for alerts
  • About us
    • About JCS
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Fast-track manuscripts
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • JCS Prize
    • Manuscript transfer network
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contacts
    • Contact JCS
    • Subscriptions
    • Advertising
    • Feedback

Cell death

  • RESEARCH ARTICLE
    Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells
    Claudio Bussi, Javier M. Peralta Ramos, Daniela S. Arroyo, Jose I. Gallea, Paolo Ronchi, Androniki Kolovou, Ji M. Wang, Oliver Florey, Maria S. Celej, Yannick Schwab, Nicholas T. Ktistakis, Pablo Iribarren
    Journal of Cell Science 2018 131: jcs226241 doi: 10.1242/jcs.226241 Published 30 November 2018

    Summary: Autophagy dynamics of microglial cells stimulated with the neuropathogenic protein alpha-synuclein (AS) show that autophagy is activated as a response to control AS-induced lysosomal damage.

  • RESEARCH ARTICLE
    Chronic starvation induces noncanonical pro-death stress granules
    Lucas C. Reineke, Shebna A. Cheema, Julien Dubrulle, Joel R. Neilson
    Journal of Cell Science 2018 131: jcs220244 doi: 10.1242/jcs.220244 Published 5 October 2018

    Summary: This work characterizes the mechanisms of formation of a novel type of stress granule that is induced in response to long-term starvation and, unlike previously described stress granules, functions in a pro-death capacity.

  • REVIEW
    Autophagy-dependent cell death – where, how and why a cell eats itself to death
    Shani Bialik, Santosh K. Dasari, Adi Kimchi
    Journal of Cell Science 2018 131: jcs215152 doi: 10.1242/jcs.215152 Published 20 September 2018

    Summary: A review of recent findings that demonstrate autophagy-dependent cell death in various contexts and begin to elucidate molecular mechanisms that render autophagy a lethal process.

  • CELL SCIENCE AT A GLANCE
    Inflammasome activation and assembly at a glance
    Ankit Malik, Thirumala-Devi Kanneganti
    Journal of Cell Science 2017 130: 3955-3963; doi: 10.1242/jcs.207365

    Summary: This article and accompanying poster provides an outline of the concepts in the assembly of inflammasomes and cell death by pyroptosis.

  • RESEARCH ARTICLE
    The initiator caspase Dronc plays a non-apoptotic role in promoting DNA damage signalling in D. melanogaster
    Chaitali Khan, Sonia Muliyil, Champakali Ayyub, Basuthkar J. Rao
    Journal of Cell Science 2017 130: 2984-2995; doi: 10.1242/jcs.200782

    Summary: Our study uncovers a novel function of Dronc in mediating the γH2Av response via ATM kinase, which, independent of its cell death function, facilitates DNA damage signalling and perhaps repair.

  • RESEARCH ARTICLE
    Phosphorylation of XIAP by CDK1–cyclin-B1 controls mitotic cell death
    Ying Hou, Lindsey A. Allan, Paul R. Clarke
    Journal of Cell Science 2017 130: 502-511; doi: 10.1242/jcs.192310

    Summary: Phosphorylation of XIAP by CDK1–cyclin-B1 controls the onset of mitotic cell death, which is important for surveillance against defects in mitosis and the response to cancer drugs that target cell division.

  • RESEARCH ARTICLE
    Efferocytosis and extrusion of leukocytes determine the progression of early mycobacterial pathogenesis
    Rohola Hosseini, Gerda E. M. Lamers, Hiwa M. Soltani, Annemarie H. Meijer, Herman P. Spaink, Marcel J. M. Schaaf
    Journal of Cell Science 2016 129: 3385-3395; doi: 10.1242/jcs.135194

    Highlighted Article: Mycobacterial infection in zebrafish larvae was explored using a combination of light and electron microscopy. Macrophage burst events resulted in a progression of infection, whereas epithelium-mediated extrusion of infected immune cells abated infection.

  • RESEARCH ARTICLE
    The selective inhibition of protein phosphatase-1 results in mitotic catastrophe and impaired tumor growth
    Claudia Winkler, Sofie De Munter, Nele Van Dessel, Bart Lesage, Ewald Heroes, Shannah Boens, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
    Journal of Cell Science 2015 128: 4526-4537; doi: 10.1242/jcs.175588

    Highlighted Article: Mitosis is an established target for cancer chemotherapy. We show that the inhibition of protein phosphatase PP1 causes an arrest in mid-mitosis that often culminates in cell death.

  • RESEARCH ARTICLE
    Neuron‐type‐specific signaling by the p75NTR death receptor is regulated by differential proteolytic cleavage
    Annalisa Vicario, Lilian Kisiswa, Jason Y. Tann, Claire E. Kelly, Carlos F. Ibáñez
    Journal of Cell Science 2015 128: 1507-1517; doi: 10.1242/jcs.161745
  • RESEARCH ARTICLE
    PARP1-mediated necrosis is dependent on parallel JNK and Ca2+/calpain pathways
    Diana L. Douglas, Christopher P. Baines
    Journal of Cell Science 2014 127: 4134-4145; doi: 10.1242/jcs.128009

Pages

  • Next
  • 1
  • 2

Other subject collections

Articles

  • Accepted manuscripts
  • Latest complete issue
  • Issue archive
  • Archive by article type
  • Special issues
  • Subject collections
  • Interviews
  • Sign up for alerts

About us

  • About Journal of Cell Science
  • Editors and Board
  • Editor biographies
  • Travelling Fellowships
  • Grants and funding
  • Journal Meetings
  • Workshops
  • The Company of Biologists

For Authors

  • Submit a manuscript
  • Aims and scope
  • Presubmission enquiries
  • Fast-track manuscripts
  • Article types
  • Manuscript preparation
  • Cover suggestions
  • Editorial process
  • Promoting your paper
  • Open Access
  • JCS Prize
  • Manuscript transfer network
  • Biology Open transfer

Journal Info

  • Journal policies
  • Rights and permissions
  • Media policies
  • Reviewer guide
  • Sign up for alerts

Contacts

  • Contact JCS
  • Subscriptions
  • Advertising
  • Feedback

Twitter   YouTube   LinkedIn

© 2021   The Company of Biologists Ltd   Registered Charity 277992