Cell growth
- Nutrient regulation of mTORC1 at a glance
Summary: A summary of how extracellular and intracellular signals feed into the mTOR pathway, how the lysosome acts as an mTOR signaling hub, and how downstream signaling controls autophagy and lysosome biogenesis.
- Nutritional cell cycle reprogramming reveals that inhibition of Cdk1 is required for proper MBF-dependent transcription
Summary: In nitrogen-poor medium, inhibition of Cdk1 becomes essential for generating a proper wave of MBF-dependent transcription at G1/S, which prevents DNA replication stress.
- Genome-wide screen for cell growth regulators in fission yeast
Summary: Using a novel system to identify cell growth regulators, we have discovered a number of factors that activate growth in cells in which growth is developmentally switched off.