Ceramide
- Autophagy-dependent cell death – where, how and why a cell eats itself to death
Summary: A review of recent findings that demonstrate autophagy-dependent cell death in various contexts and begin to elucidate molecular mechanisms that render autophagy a lethal process.
- The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast
Summary: A characterization of fission yeast temperature-sensitive mutants of the putative ceramide-conjugation protein Cwh43, is presented in order to explore its relevance to utilization of glucose, nitrogen source and lipids.
- Acid sphingomyelinase is required for cell surface presentation of Met receptor tyrosine kinase in cancer cells
Summary: Acid sphingomyelinase (ASM) regulates the cell surface levels of Met receptor tyrosine kinase through selective regulation of the exit of Met from the Golgi.