Cx43
- Identification of serine residues in the connexin43 carboxyl tail important for BCR-mediated spreading of B-lymphocytes
Summary: Mutation of specific serine residues of connexin43 affects B-cell spreading, suggesting that this protein can be considered as a regulator of B-cell responses.
- Mice harbouring an oculodentodigital dysplasia-linked Cx43 G60S mutation have severe hearing loss
Summary: Mutant mice harbouring a severe loss-of-function mutation in Gja1, encoding Cx43, that is associated with the human-linked disease oculodentodigital dysplasia, leads to severe hearing loss and central auditory defects.