FGF
- Number and brightness analysis reveals that NCAM and FGF2 elicit different assembly and dynamics of FGFR1 in live cells
Summary: FGFR1 clustering is differentially regulated by the two ligands NCAM and FGF2 in live cells, as revealed by number of molecules and brightness (N&B) analysis.
- Multiple roles of epithelial heparan sulfate in stomach morphogenesis
Summary: Heparan sulfate is highly expressed in the embryonic mammalian stomach and is required for gastric development, including stratification of forestomach and specification of glandular stomach.
- FGF2 inhibits endothelial–mesenchymal transition through microRNA-20a-mediated repression of canonical TGF-β signaling
Summary: FGF2 induces the expression of miR-20a, which targets the TGFβ receptor complex and abolishes endothelial–mesenchymal transition, a process that has a major role in fibroproliferative diseases.
- FGF control of E-cadherin targeting in the Drosophila midgut impacts on primordial germ cell motility
Summary: FGF signaling modulates zygotic E-cadherin distribution to maintain posterior midgut epithelial 3D architecture, impacting on primordial germ cell motility during Drosophila early embryonic development.