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Heat stress

  • RESEARCH ARTICLE
    Sequestration of the PKC ortholog Pck2 in stress granules as a feedback mechanism of MAPK signaling in fission yeast
    Yuki Kanda, Ryosuke Satoh, Teruaki Takasaki, Naofumi Tomimoto, Kiko Tsuchiya, Chun An Tsai, Taemi Tanaka, Shu Kyomoto, Kozo Hamada, Toshinobu Fujiwara, Reiko Sugiura
    Journal of Cell Science 2021 134: jcs250191 doi: 10.1242/jcs.250191 Published 26 January 2021

    Summary: Pmk1 regulates Pck2 recruitment into stress granules (SGs) upon heat stress, which intercepts MAPK signaling activation, indicating that SGs sequester active Pck2 in a feedback mechanism.

  • RESEARCH ARTICLE
    TORC2 mediates the heat stress response in Drosophila by promoting the formation of stress granules
    Irena Jevtov, Margarita Zacharogianni, Marinke M. van Oorschot, Guus van Zadelhoff, Angelica Aguilera-Gomez, Igor Vuillez, Ineke Braakman, Ernst Hafen, Hugo Stocker, Catherine Rabouille
    Journal of Cell Science 2015 128: 2497-2508; doi: 10.1242/jcs.168724

    Highlighted Article: The Drosophila TOR complex 2 is necessary for the formation of heat-induced cytoprotective stress granules, which can explain the heat sensitivity of TORC2 mutant flies.

  • RESEARCH ARTICLE
    Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-κB activation
    Bihui Zhong, Qin Zhou, Diana M. Toivola, Guo-Zhong Tao, Evelyn Z. Resurreccion, M. Bishr Omary
    Journal of Cell Science 2004 117: 1709-1719; doi: 10.1242/jcs.01016

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