Hepatocyte
- Keratin impact on PKCδ- and ASMase-mediated regulation of hepatocyte lipid raft size – implication for FasR-associated apoptosis
Summary: Hepatocytes express keratin 8 (K8) and 18 (K18) as their sole intermediate filaments. A loss of K8/K18 impacts on PKCδ- and ASMase-mediated modulation of lipid raft size and FasR-mediated apoptosis.
- Myosin Vb mediates Cu+ export in polarized hepatocytes
Summary: Myosin Vb regulates Cu+-induced recycling of ATP7B at the apical membrane in polarized hepatocytes.