Infection
- Viral use and subversion of membrane organization and trafficking
Summary: This Review at the intersection of membrane trafficking and virology discusses how viruses hijack the organisation and function of cellular membranes to accomplish their replication, assembly and egress.
- Regulation of kinesin-1 activity by the Salmonella enterica effectors PipB2 and SifA
Summary: The kinesin-1 motor protein plays a key role in controlling the membrane exchanges necessary for the intracellular survival of Salmonella. The complexity of kinesin-1 regulation by Salmonella effector proteins is highlighted.
- Efferocytosis and extrusion of leukocytes determine the progression of early mycobacterial pathogenesis
Highlighted Article: Mycobacterial infection in zebrafish larvae was explored using a combination of light and electron microscopy. Macrophage burst events resulted in a progression of infection, whereas epithelium-mediated extrusion of infected immune cells abated infection.