Late endosome
- The enigmatic endosome – sorting the ins and outs of endocytic trafficking
Summary: This Review will attempt to collate key characteristics of the different types of endosomes and provide a platform for discussion of this unique and fascinating collection of organelles.
- A proteomic approach to identify endosomal cargoes controlling cancer invasiveness
Highlighted Article: This paper describes a novel proteomic approach to identify pro-invasive cargoes, which we have used to determine that Rab17 controls Vamp8 levels to drive neuropilin-2 trafficking, promoting invasion.
- Mechanisms and functions of lysosome positioning
Summary: We review recent findings on the mechanisms that mediate the motility and positioning of lysosomes, and the importance of lysosome dynamics for cell physiology and pathology.