Membrane contact site
- Role of the Sec22b–E-Syt complex in neurite growth and ramification
Highlighted Article: The non-fusogenic Sec22b–Stx1 SNARE complex contributes to plasma membrane expansion by interacting with the E-Syt lipid transfer proteins at ER–PM contact sites.
- RDGBα localization and function at membrane contact sites is regulated by FFAT–VAP interactions
Summary: FFA–VAP interactions regulate lipid transfer activity in Drosophila photoreceptors during PLC signalling.
- Junctate boosts phagocytosis by recruiting endoplasmic reticulum Ca2+ stores near phagosomes
Highlighted Article: The STIM1-interacting protein junctate generates Ca2+ hotspots that boost phagocytosis independently of STIM1 by promoting Ca2+ release from ER stores rather than by gating phagosomal Ca2+ channels.