MMP9
- The armadillo protein p0071 controls KIF3 motor transport
Summary: The armadillo protein p0071 controls directional vesicular transport mediated by the KIF3 (kinesin-2) complex, and secretion of respective cancer-relevant cargos from neuroendocrine and pancreatic tumor cells.
- The role and regulation of Rab40b–Tks5 complex during invadopodia formation and cancer cell invasion
Highlighted Article: Rab40b plays a key role in mediating invadopodia function during breast cancer cell invasion by binding to Tks5 and functioning as a tether mediating MMP2 and MMP9 targeting to the extending invadopodia.
- The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration
Summary: The NMDA receptor and LRP1 function as co-receptors in Schwann cells, activating cell signaling in response to protein ligands and promoting cell survival and migration.