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Nuclear mechanical response

  • REVIEW
    Emerging roles of mechanical forces in chromatin regulation
    Yekaterina A. Miroshnikova, Michele M. Nava, Sara A. Wickström
    Journal of Cell Science 2017 130: 2243-2250; doi: 10.1242/jcs.202192

    Summary: This Review discusses the mechanisms by which the nucleus, and chromatin in particular, respond to changes in the mechanical microenvironment of the cell, resulting in architectural and transcriptional alterations, and thereby facilitating cellular adaption.

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