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Oligodendrocyte

  • RESEARCH ARTICLE
    PTPα is required for laminin-2-induced Fyn–Akt signaling to drive oligodendrocyte differentiation
    Philip T. T. Ly, Craig Stewart, Catherine J. Pallen
    Journal of Cell Science 2018 131: jcs212076 doi: 10.1242/jcs.212076 Published 6 August 2018

    Summary: The receptor PTPα is an essential component of integrin and dystroglycan receptor complexes that transduce extrinsic laminin-2 signals into specific intracellular events to promote OL differentiation.

  • RESEARCH ARTICLE
    Dual role of the RNA helicase DDX5 in post-transcriptional regulation of myelin basic protein in oligodendrocytes
    Peter Hoch-Kraft, Robin White, Stefan Tenzer, Eva-Maria Krämer-Albers, Jacqueline Trotter, Constantin Gonsior
    Journal of Cell Science 2018 131: jcs204750 doi: 10.1242/jcs.204750 Published 1 May 2018

    Summary: The RNA helicase DDX5 is a novel component of heterogeneous complexes containing Mbp mRNA, regulating post-transcriptional expression of MBP levels and isoform ratios in oligodendrocytes.

  • RESEARCH ARTICLE
    MOBP levels are regulated by Fyn kinase and affect the morphological differentiation of oligodendrocytes
    Isabelle Schäfer, Christina Müller, Heiko J. Luhmann, Robin White
    Journal of Cell Science 2016 129: 930-942; doi: 10.1242/jcs.172148

    Summary: In oligodendrocytes, Fyn kinase regulates the synthesis of MOBP, and MOBP is required for establishing the complex cellular morphology of oligodendrocytes.

  • RESEARCH ARTICLE
    Transport and translation of MBP mRNA is regulated differently by distinct hnRNP proteins
    Julie Torvund-Jensen, Jes Steengaard, Lasse Reimer, Linda B. Fihl, Lisbeth S. Laursen
    Journal of Cell Science 2014 127: 1550-1564; doi: 10.1242/jcs.140855

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