Plasmodium falciparum
- Plasmodium falciparum GCN5 acetyltransferase follows a novel proteolytic processing pathway that is essential for its function
Highlighted Article: Proteolytic processing of the nuclear GCN5 histone acetyltransferase by a cysteine protease-like enzyme in the vicinity of the food vacuole is important for its function in Plasmodium falciparum.
- The RNA-binding protein Puf1 functions in the maintenance of gametocytes in Plasmodium falciparum
Highlighted Article: Characterization of the RNA-binding protein Puf1 as an important regulator required for the maintenance of late-stage gametocytes, the sexual form required for transmission to mosquitoes, in the malaria parasite.
- Localisation-based imaging of malarial antigens during erythrocyte entry reaffirms a role for AMA1 but not MTRAP in invasion
Highlighted Article: Here we develop a high-definition imaging approach to dissect and assign function to proteins involved in the rapid process of malaria parasite invasion of the human erythrocyte.