RAB5
- The EGFR odyssey – from activation to destruction in space and time
Summary: We review the molecular events that occur during EGFR activation, its trafficking through the endosomal system and its subsequent downregulation.
- Retrograde transport is not required for cytosolic translocation of the B-subunit of Shiga toxin
Summary: Retrograde transport is not required for cytosolic translocation of the B-subunit of Shiga toxin, revealing new facets of the endosomal escape process with relevance to antigen cross-presentation.