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RAGE

  • RESEARCH ARTICLE
    Sensory neuronal sensitisation occurs through HMGB-1–RAGE and TRPV1 in high-glucose conditions
    Samuel M. Bestall, Richard P. Hulse, Zoe Blackley, Matthew Swift, Nikita Ved, Kenneth Paton, Nicholas Beazley-Long, David O. Bates, Lucy F. Donaldson
    Journal of Cell Science 2018 131: jcs215939 doi: 10.1242/jcs.215939 Published 26 July 2018

    Summary: In high-glucose conditions, nociceptive neurons are sensitised through the actions of HMGB1 acting though RAGE and PKC. This sensitisation is blocked by a VEGF-A splice variant.

  • RESEARCH ARTICLE
    RAGE signaling deficiency in rhabdomyosarcoma cells causes upregulation of PAX7 and uncontrolled proliferation
    Francesca Riuzzi, Guglielmo Sorci, Roberta Sagheddu, Angelo Sidoni, Rita Alaggio, Vito Ninfo, Rosario Donato
    Journal of Cell Science 2014 127: 1699-1711; doi: 10.1242/jcs.136259

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