Regulated exocytosis
- Real-time insights into regulated exocytosis
Summary: This Commentary focuses on recent developments in three-dimensional time-lapse imaging of regulated secretion occurring in living secreting organs.
- Rab2a and Rab27a cooperatively regulate the transition from granule maturation to exocytosis through the dual effector Noc2
Summary: Although regulated exocytosis comprises several sequential steps, the mechanisms coordinating each step are poorly understood. These findings suggest that Noc2 regulates the transition between Rab2a- and Rab27a-mediated exocytosis.