RNA-binding proteins
- How alternative splicing affects membrane-trafficking dynamics
Summary: This Review summarizes how trafficking is molecularly influenced by alternative splicing and how this interplay impacts physiology and pathological conditions.
- RNA tales – how embryos read and discard messages from mom
Summary: After fertilization, transcriptionally silent embryos are driven by maternal RNA; recently revealed mechanisms explain how mRNA stability and translation are highly regulated and coordinated with the transition to zygotic control.
- Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast
Summary: The RNA-binding protein Zfs1 regulates accumulation of the G1 cyclin Puc1, a process that is modulated by phosphorylation. This regulatory mechanism has an important impact on cell differentiation.
- Localized translation regulates cell adhesion and transendothelial migration
Summary: Translation affects adhesion and invasion potential of spreading initiation centers (SICs) producing mesenchymal cells, but not epithelial cells, which are deprived of SICs