Signaling pathways
- Mapping growth-factor-modulated Akt signaling dynamics
Summary: Using real-time tracking of a fluorescent sensor molecule, these studies address signaling specificity by determining how actions of different growth factors are encoded into distinct Akt signaling dynamics.
- Decoding the stem cell quiescence cycle – lessons from yeast for regenerative biology
Summary: This Opinion article examines key concepts underlying our understanding of stem cell quiescence that can be attributed to studies in yeast.
- Akt signaling dynamics in individual cells
Summary: Description of a simple and dynamic measure of Akt signaling activity in living cells that will provide new insights into how Akt regulates its biological responses.