SMN
- Neurochondrin interacts with the SMN protein suggesting a novel mechanism for spinal muscular atrophy pathology
Highlighted Article: The essential neural protein neurochondrin interacts with the spinal muscular atrophy (SMA) protein SMN in cell lines and in mice. This might be relevant to the molecular pathology of SMA.
- SMN affects membrane remodelling and anchoring of the protein synthesis machinery
Summary: SMN is shown to affect membrane dynamics. We propose that SMN assembles a translational platform associated to and governed by plasma membrane.