Stress fibers
- Cellular strain avoidance is mediated by a functional actin cap – observations in an Lmna-deficient cell model
Summary: The strain avoidance response of cells lacking a functional actin cap, such as in Lmna-deficient cells, is impaired. This suggests a crucial role for the actin cap in strain responsiveness.
- The inner workings of stress fibers − from contractile machinery to focal adhesions and back
Summary: Ventral stress fibers play a key role in cellular mechanosensitivity. We discuss here fundamental questions regarding their structure, force-dependent assembly and force generation capacity.
- Caveolae – mechanosensitive membrane invaginations linked to actin filaments
Summary: Caveolae and stress fibers are two essential players in the cell response to mechanical forces. The physical association of these two mechanosensors could ensure a coordinated response during mechanotransduction.