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Journal of Cell Science

Trio

RESEARCH ARTICLE

A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1
Ilse Timmerman, Niels Heemskerk, Jeffrey Kroon, Antje Schaefer, Jos van Rijssel, Mark Hoogenboezem, Jakobus van Unen, Joachim Goedhart, Theodorus W. J. Gadella, Jr, Taofei Yin, Yi Wu, Stephan Huveneers, Jaap D. van Buul

Journal of Cell Science 2015 128: 3041-3054; doi: 10.1242/jcs.168674

Highlighted Article: The Rho-GEF Trio controls the stability of endothelial cell–cell junctions by locally activating the GTPase Rac1 at VE-cadherin-based junctions. Loss of Trio increases focal adherens junctions and electrical resistance.
RESEARCH ARTICLE

Notch directly regulates the cell morphogenesis genes Reck, talin and trio in adult muscle progenitors
Guillaume Pézeron, Kat Millen, Hadi Boukhatmi, Sarah Bray

Journal of Cell Science 2014 127: 4634-4644; doi: 10.1242/jcs.151787