WAVE
- Cellular functions of WASP family proteins at a glance
Summary: This article provides insight into new functions of WASP family proteins from regulating the biogenesis of autophagosomes to recently identified roles in the nucleus.
- Direct interaction between exocyst and Wave complexes promotes cell protrusions and motility
Highlighted Article: A direct link between exocyst and Wave complexes is revealed, providing new mechanistic insight into the spatio-temporal coordination between membrane trafficking and actin polymerization.
- Drosophila Kette coordinates myoblast junction dissolution and the ratio of Scar-to-WASp during myoblast fusion
Summary: The Drosophila protein Kette is essential for myoblast fusion. It controls the dissolution of electron-dense plaques and the ratio of Scar and WASp proteins in fusion-competent myoblasts during fusion pore formation.
- Meiotic onset is reliant on spatial distribution but independent of germ cell number in the mouse ovary
Summary: Germ cell numbers do not affect the wave of meiotic entry in female mice. Migration mutants support a diffusion model of meiotic entry and connect aberrant germ cell migration to defects in meiosis.
- WHAMY is a novel actin polymerase promoting myoblast fusion, macrophage cell motility and sensory organ development in Drosophila
Summary: Here, we characterize WHAMY, the fourth member of the Drosophila WASP family. We found that WHAMY is a novel actin polymerase.